American Airlines frequently offers competitive one-stop service from Blue Grass Airport (LEX) to El Paso International Airport (ELP) via Dallas/Fort Worth, often providing numerous daily connection options. United Airlines routes may connect through Houston (IAH) or Chicago (ORD) and can be a good choice for MileagePlus members. Delta Air Lines connects via Atlanta (ATL) or Charlotte (CLT) depending on schedules. Consider baggage allowances, change/cancellation policies, and loyalty benefits: American may have the most seamless DFW connections, United can offer good reliability via IAH, and Delta often provides robust schedule options via ATL. For September travel, check each airline’s sale fares, baggage rules, and hub connection times before booking. CTA: Compare fares and benefits now to choose the best carrier for your September Lexington to El Paso trip.