October at McGhee Tyson Airport (TYS) marks prime fall travel for leaf-peeping and festivals across East Tennessee. Demand can rise on long weekends for Great Smoky Mountains National Park, Pigeon Forge, and Gatlinburg, so book flights early. For travelers flying to Cleveland Hopkins International Airport (CLE), expect mostly one-stop itineraries through Atlanta, Charlotte, Detroit, or Chicago — search 'TYS to CLE flights' and compare carriers for the best fare. Local transit and parking are reliable in October; rideshares, shuttles, and rental cars are recommended for flexible regional travel. Nearby major cities commonly accessed from TYS include Nashville (Nashville, TN), Chattanooga (Chattanooga, TN), Asheville (Asheville, NC), Gatlinburg (Pigeon Forge/Gatlinburg area), and Atlanta (Atlanta, GA). CTA: Compare October TYS to CLE flights now and set airfare alerts to lock in the best fares during fall travel season.
October landing at Cleveland Hopkins International Airport (CLE) is ideal for fall city breaks and regional drives to see foliage across Northeast Ohio. Expect cooler temperatures and occasional rain; pack a light jacket and plan transportation ahead of time. Popular nearby cities accessed from CLE include Akron, Canton, Youngstown, Pittsburgh, and Columbus—making CLE a convenient hub for multi-city fall itineraries. If you're arriving from McGhee Tyson Airport (TYS), check your connection timings, as most flights are one-stop through major hubs. CTA: Book CLE arrival transfers and compare October car rental rates now to secure the best local deals.
October brings vibrant events near both airports. Near McGhee Tyson Airport (TYS): Great Smoky Mountains fall foliage peaks (early–mid October in lower elevations, mid–late October in higher elevations), Pigeon Forge and Gatlinburg Harvest Festivals, and the Jonesborough National Storytelling Festival held in October in nearby Jonesborough. Near Cleveland Hopkins International Airport (CLE): Oktoberfest and local brewery festivals, fall harvest events in the Cleveland Metroparks, and occasional sporting highlights (Cleveland Guardians/Browns) depending on the season. These events can increase flight and hotel demand—book early if you plan to attend. CTA: Check event dates before booking TYS to CLE flights in October to get the best rates and seat availability.
Midweek flights (Tuesday–Thursday) and early-morning departures are typically the best time to fly from McGhee Tyson Airport (TYS) to Cleveland Hopkins International Airport (CLE) in October for lower fares and fewer crowds. Avoid holiday weekends and local festival dates—weekend demand spikes due to leaf-peeping and regional events. For business travelers, Monday morning returns and Friday afternoons are busier and often more expensive. If you want both savings and pleasant travel, target a midweek, off-peak flight and set fare alerts several weeks ahead. CTA: Search flexible dates for TYS to CLE October travel to find the best balance of price and convenience.
On the McGhee Tyson Airport (TYS) to Cleveland Hopkins International Airport (CLE) corridor, nonstop flights are rare; one-stop connecting flights are the norm. Direct (nonstop) flights save time and reduce connection risk, but they may be unavailable or more expensive when they exist. Connecting flights via hubs such as Atlanta (ATL), Charlotte (CLT), Detroit (DTW), or Chicago (ORD) often offer more schedule flexibility and lower fares, especially in October. Choose connecting itineraries with reliable carriers and allow 60–90 minutes for domestic transfers to minimize missed-connection risk. CTA: Compare nonstop and one-stop TYS to CLE flights and filter by shortest total travel time or lowest price.
Delta Air Lines: Often routes TYS to CLE via Atlanta (ATL). Pros: frequent connections, strong on-time performance, robust domestic network. Cons: sometimes higher fares on premium connections. American Airlines: Common connections through Charlotte (CLT) or Philadelphia (PHL). Pros: wide network, good option for AAdvantage members. Cons: variable connection times depending on routing. United Airlines: Typical one-stops via Chicago (ORD) or Washington (IAD). Pros: multiple routing options and MileagePlus benefits. Cons: ORD connections can be subject to winter weather delays later in the season. Southwest: Limited direct service between TYS and CLE; use Southwest for flexible fares if available via alternative routing. CTA: Compare fares by routing and total travel time to pick the best airline for your October TYS to CLE trip.
Pack layers: October temperatures range from mild in Knoxville to cooler in Cleveland, especially evenings—bring a light jacket and an umbrella. Allow extra connection time when routing through busy hubs and factor in earlier sunsets that can affect ground travel after arrival. For leaf-peeping, plan drives to higher elevations later in October for peak color in the Smokies. Reserve rental cars and parking in advance for weekend travel, and sign up for airline alerts and TSA PreCheck to speed airport processing. Finally, check local event calendars for both Knoxville and Cleveland to avoid high-demand travel dates. CTA: Prepare for October travel now—compare TYS to CLE flights, reserve cars, and book parking to avoid last-minute hassles.
There are few nonstop options between McGhee Tyson Airport (TYS) and Cleveland Hopkins International Airport (CLE); most itineraries are one-stop. Typical total travel time ranges from 3.5 to 6+ hours depending on connection durations. Common connection hubs include Atlanta (ATL), Charlotte (CLT), Detroit (DTW), and Chicago (ORD). Weekday flights often provide the most options for one-stop scheduling, while weekend schedules may be more limited—book earlier for weekend travel in October. For time-sensitive trips, target connections with at least 60–90 minutes for domestic transfers to reduce risk of missed connections. CTA: Check current TYS to CLE flight schedules and sort by shortest total travel time.
To score cheap flights from McGhee Tyson Airport (TYS) to Cleveland Hopkins International Airport (CLE) in October, prioritize flexible dates and midweek travel—Tuesdays and Wednesdays often offer lower fares. Set price alerts on multiple aggregators and compare one-stop routing through Atlanta (ATL), Charlotte (CLT), Detroit (DTW), or Chicago (ORD) to find the lowest connection fares. Book 3–6 weeks ahead for non-holiday October travel; last-minute deals sometimes appear but are less reliable during fall festivals. Consider red-eye departures, alternate nearby airports, or refundable fares if schedules may shift. CTA: Use fare alerts and compare 'TYS to CLE flights' to lock in October savings.