Direct (nonstop) flights from San Francisco International Airport (SFO) to Ninoy Aquino International Airport (MNL) save significant travel time (roughly 13–14 hours) and reduce complexity, but they can be priced higher and may be seasonal. Connecting itineraries via Tokyo, Seoul, Hong Kong, or Taipei often lower the fare and expand schedule options but add layover time (total travel often 16–24+ hours). If convenience and sleep on a long-haul matter, prioritize nonstop flights; if price or routing flexibility is key, compare one-stop options. CTA: Filter search results for nonstop if you prefer direct SFO to MNL service, or compare one-stop savings.