Choosing between nonstop and connecting flights from Seattle-Tacoma International Airport (SEA) to Tampa International Airport (TPA) in March depends on time, budget, and availability. Nonstop flights (when available) reduce travel time to about 5.5–6 hours and lower the risk of missed connections, but they often carry a price premium during high-demand March weeks. Connecting flights via hubs like DEN, ATL, MSP, and ORD are usually cheaper and offer more scheduling options but increase total travel time and add potential layover risks. For tight itineraries, prioritize nonstops; for savings and flexibility, opt for one-stop flights and select reliable layovers of at least 90 minutes.