Major U.S. carriers (Delta, United, American) and Asian carriers (Korean Air, Japan Airlines, Philippine Airlines partners) are commonly used for journeys from Raleigh-Durham International Airport (RDU) to Ninoy Aquino International Airport (MNL). Delta often routes via Atlanta (ATL) and uses SkyTeam partners for the transpacific leg, United routes via Newark/Chicago with Star Alliance partners, and American routes via New York or Charlotte with Oneworld connections. Korean Air and Japan Airlines provide strong Asian hub connectivity (ICN, NRT) with good service standards on long-haul segments. For October travel, compare baggage policies, seat availability in premium economy or business, and alliance benefits. Use keywords like 'best airline RDU to MNL October' to find route-specific promotions. CTA: Compare airlines and read recent passenger reviews before booking your October trip.