Major carriers serving PIT to MCO include Southwest, American, and Delta, with each offering a different balance of price, schedules, and perks in April. Southwest often offers competitive bundle-free fares with two free checked bags, making it attractive for families and longer stays. American Airlines may provide more early-morning and late-evening nonstop options on select days, while Delta offers strong connectivity via ATL for tighter connections or loyalty benefits. Compare total cost including baggage, seat selection, and change fees when choosing the best airline for your April trip.