Major carriers operating service between the Philadelphia area (PHLA) and San Francisco International Airport (SFO) in November include American Airlines (often offering nonstop service), United Airlines (via hubs like Chicago), Delta Air Lines (via Atlanta or Detroit), and Alaska Airlines (via connecting hubs). American tends to provide strong east–west nonstop offerings from Philadelphia, with competitive business class and loyalty perks. United and Delta often have more connecting schedules and wider hub choices that can lower fares. Alaska is known for competitive pricing and customer service on West Coast routes when connections line up. Compare baggage allowances, loyalty programs (AAdvantage, MileagePlus, SkyMiles, Mileage Plan), seat selection fees, and onboard amenities. CTA: Compare November fares and policies across airlines to find the best PHLA–SFO experience for your budget and loyalty status.