American Airlines: Often connects via Dallas/Fort Worth (DFW) or Charlotte (CLT), competitive fares, broad domestic network, and perks for AAdvantage members. Delta Air Lines: Commonly routes through Atlanta (ATL), strong on-time performance in many markets and Medallion benefits for elite flyers. United Airlines: Typical connections through Houston (IAH) or Chicago (ORD), MileagePlus benefits, and extensive partner flights. Alaska Airlines: Hub strength at Seattle–Tacoma International Airport (SEA) makes it a desirable carrier for Pacific Northwest segments; however, from Mobile you’ll likely connect onto Alaska codeshares via partner carriers. For November travel, compare connection durations, baggage fees, and loyalty benefits — choose the carrier and connection city that best balances cost and minimum connection times. CTA: Compare multi-carrier itineraries and loyalty options before booking MOB to SEA flights this November.