Major carriers that commonly serve Harrisburg International Airport (MDT) and Manchester-Boston Regional Airport (MHT) include American Airlines, Delta Air Lines, and United Airlines, with low-cost and seasonal operators sometimes offering alternate routing or fares. American typically connects through Philadelphia (PHL), Delta through hubs like Detroit (DTW) or Atlanta (ATL) depending on routing, and United often connects via Newark (EWR) or Chicago (ORD). Baggage fees, seat selection, and loyalty benefits vary—budget-conscious travelers should compare basic economy vs main cabin, while frequent flyers may prioritize a carrier with better elite benefits. In November, check seasonal schedule changes, de-icing procedures, and holiday fee waivers or promotions. CTA: Compare airline options and baggage rules now to choose the best November itinerary between Harrisburg International Airport (MDT) and Manchester-Boston Regional Airport (MHT).