October departures from Orlando International Airport (MCO) to St. Louis Lambert International Airport (STL) are influenced by Florida fall events and lower hurricane-season activity. Expect a steady schedule of daily nonstop flights as well as connecting options; book 3–8 weeks in advance for the best autumn fares. For Halloween travelers attending Universal’s Halloween Horror Nights or theme-park seasonal events, plan your arrival at the airport earlier in the day and consider TSA PreCheck or expedited security services. Nearby cities commonly accessed from MCO include Orlando, Kissimmee, Tampa, Miami, Daytona Beach, and Cape Canaveral — handy if you’re combining a Florida getaway before a flight to St. Louis. Use fare alerts and mid-week departure windows to find the most competitive October prices; CTA: Search MCO to STL flights for October now to compare nonstop and budget options.
Arriving at St. Louis Lambert International Airport (STL) in October is ideal for travelers who want cool fall weather, city festivals, and easier access to attractions like the Gateway Arch and Forest Park. Flights from Orlando International Airport (MCO) typically land throughout the day; plan ground travel into downtown St. Louis, Clayton, Belleville (IL), or even Branson and Springfield for longer road trips. October offers leaf-peeping and Oktoberfest events across the region, so reserve rental cars and hotels early if attending major festivals. CTA: Book your MCO to STL arrival transfer for October to lock in early-bird rental car and shuttle rates.