Common airline options for the Orlando International Airport (MCO) to Hong Kong International Airport (HKG) route in October include U.S. majors (United, American, Delta) with partner or codeshare long-haul segments, Asian carriers (Cathay Pacific via U.S. gateways, EVA Air via Taipei, ANA/JAL via Tokyo), and Middle Eastern carriers (Qatar Airways, Emirates) offering 2-stop itineraries. Cathay Pacific (via partner connections) often provides high-quality onboard service and direct transpacific legs from West Coast hubs; EVA and ANA can be competitive for connections through Taipei or Tokyo. Middle Eastern carriers may offer greater comfort but longer total travel times. Compare total journey time, checked-baggage allowances, and alliance benefits when booking, and search for October promos or partner-award availability to optimize price and service.