For travel from Los Angeles International Airport (LAX) to Ellison Onizuka Kona International at Keahole (KOA) in October, Hawaiian Airlines often provides the most nonstop frequency and island-focused service, including complimentary meals on some transpacific flights and robust inter-island connections. Alaska Airlines and American Airlines also operate routes to Kona, sometimes offering seasonal nonstops or one-stop connections via West Coast hubs. Delta Air Lines and United Airlines provide connecting itineraries through their hubs. Evaluate seat comfort, baggage allowances, loyalty benefits, and schedule convenience when choosing: Hawaiian for nonstop convenience and island connectivity, Alaska and American for competitive pricing and loyalty partnerships, and major network carriers for broader connection options.