September offers rich event calendars at both ends of the route. Near Indianapolis International Airport (IND), look for fall fairs, cultural festivals, and the beginning of college football season that bring regional visitors; downtown Indianapolis often hosts arts and food events. Around Asheville Regional Airport (AVL), September is prime for outdoor festivals, craft brewery events, early foliage drives on the Blue Ridge Parkway, and concerts at the Biltmore Estate—ideal for leaf-peeping and culinary weekends. Popular nearby destinations include downtown Indianapolis, Louisville, Charlotte, Asheville, Boone, and Gatlinburg. CTA: Check local event calendars at VisitIndy.org and VisitAVL.com when planning your September IND → AVL trip to align flights with must-see events.