Major carriers for travel between George Bush Intercontinental Airport (IAH) and José María Córdova International Airport (MDE) include United Airlines (hub at IAH), Avianca (strong Colombian network), Copa Airlines (frequent PTY connections), and American Airlines (connections via Miami). United may offer limited nonstop or single-connection options and strong loyalty benefits for U.S. flyers. Avianca often provides competitive one-stop options via Bogotá (BOG) with better domestic connectivity inside Colombia. Copa, through Panama City (PTY), is a solid value choice with reliable connections and consistent baggage allowances. American Airlines commonly connects through Miami (MIA) and can be convenient for U.S. network connections. In February, compare total trip time, checked baggage allowance, seat pitch, and fare class to choose the best carrier for your needs.