Turkish Airlines typically offers the most nonstop flights from Newark Liberty International Airport (EWR) to Istanbul Airport (IST) and includes solid long-haul service, generous checked baggage allowances, and hub connections throughout Turkey. Primary keyword: Turkish Airlines EWR IST. United Airlines may offer codeshare options and partner itineraries, while Lufthansa, British Airways, and KLM provide competitive one-stop options via major European hubs. Compare fare classes, baggage policies, and total travel time when booking. For January travel, look for Turkish Airlines promotions and consider refundable or flexible fares to guard against weather disruptions. CTA: Compare airlines and book the best January fare for flights from Newark Liberty International Airport (EWR) to Istanbul Airport (IST).