Popular choices for travel between Chicago (All Airports) (CHIA) and Guangzhou Baiyun International Airport (CAN) include major U.S. carriers with partner connections (United, American), and Asian carriers (China Southern, China Eastern, Korean Air, EVA Air) offering one-stop or seasonal nonstop services. China Southern often provides the most direct access to Guangzhou, sometimes with seasonal nonstop flights or single-stop options via domestic hubs. U.S. carriers may route through partner hubs (e.g., Los Angeles or San Francisco) requiring additional domestic legs. When comparing airlines for November travel, factor in baggage allowances, meal service, seat selection fees, elite status benefits, and on-time performance. Use alliance partnerships (Star Alliance, SkyTeam) to combine segments for smoother transfers and point accrual. CTA: Compare airlines for your November CHIA to CAN trip and check baggage rules and cancellation policies before booking.