Delta Air Lines: Advantageous for travelers departing Hartsfield-Jackson Atlanta International Airport (ATL) because Delta often provides direct or single-connection service to Rome–Fiumicino (FCO) in peak seasons. Strong ground operations at ATL and Delta Sky Club access make connections smoother. ITA Airways: Italy's flag carrier (and SkyTeam partner) offers competitive service to FCO when routing via its own European hubs or through transatlantic partnerships; may provide attractive Milan or Rome onward connections. American Airlines: Typically offers one-stop itineraries with partner airlines through U.S. and European hubs; good option for AAdvantage members seeking mileage credit. European carriers (KLM, Air France, Lufthansa): Provide reliable one-stop connections via AMS, CDG, or FRA and often present the most competitive fares in November. For comfort and time savings, choose nonstop when available; for lower fares, select reputable connecting itineraries and allow generous layover times. CTA: Compare Delta, ITA Airways and partner itineraries for November to pick the best combination of price, schedule and loyalty benefits.